Immunoassay for the qualitative detection of total antibodies (IgG and IgM) to Treponema pallidum in human serum and plasma. The test is intended as an aid in the diagnosis of syphilis infection in conjunction with clinical signs and symptoms.
Recombinant Antigen Assay
Rapid Plasma Reagin (RPR); VDRL; Treponema Pallidum; Syphillis Serology; T Pallidum Antibodies (Syphilis IgG/IgM Screen); RPR, T Pallidum Antibodies (Syphilis IgG/IgM Screen)
Serum separator tube (SST) Please allow 20 minutes after collection for specimen to clot before centrifugation. All specimens must be centrifuged within four hours of collection.
Specimen Minimum Volume
1.0 mL of blood
Specimen Stability Information
Separated serum is stable for 5 days at 2 – 8°C. Freeze for extended storage. Separate EDTA plasma from red cells and test within 48 hours of collection.
Samples should not be taken from patients receiving therapy with high biotin doses (i.e. > 5 mg/day) until at least 8 hours following the last biotin administration.
Samples with a cutoff index < 1.00 are non-reactive in the Elecsys Syphilis assay. These samples are considered negative for anti-Treponema pallidum antibodies. Samples with a cutoff index ≥ 1.00 are considered reactive in the Elecsys Syphilis assay. All initially reactive samples are repeated automatically by the analyzer. Repeatedly reactive samples must be supplemented according to recommended confirmatory algorithms. Reactive treponemal test results alone are not diagnostic of syphilis, treponemal test results should always be interpreted in conjunction with additional treponemal or nontreponemal serologic test results (as appropriate), medical history, clinical presentation and other findings, as recommended by the Centers for Disease Control and Prevention (CDC) Sexually Transmitted Diseases Treatment Guidelines.
Glens Falls Hospital Chemistry and Special Chemistry Department
Day(s) and Time(s) Performed
As ordered. Turn around time is 4 hours.
Specimen Retention Time
RPR if positive.