In vitro diagnostic test for the quantitative determination of acetaminophen overdose in serum and plasma on Roche/Hitachi cobas c systems. Acetaminophen is a widely used analgesic and antipyretic found in a number of over the counter and prescription products. When consumed in overdose quantities, acetaminophen may cause severe liver and kidney damage, or death.
The assay is based on a homogeneous enzyme immunoassay technique.
Acetaminophen; Tylenol; Datril, Acetaminophen Level
Plasma or serum
Lithium heparin plasma separator tube is preferred but serum separator tube (SST) is also acceptable. If using an SST, please allow 20 minutes after collection for specimen to clot before centrifugation. All specimens must be centrifuged within four hours of collection.
Specimen Minimum Volume
0.5 mL of blood
Specimen Stability Information
Centrifuged specimen stable for 1 week refrigerated.
Glens Falls Hospital Chemistry and Special Chemistry Department
Therapeutic range: 10-30 ug/mL Hepatotoxicity possible at the following levels: >= 150 ug/mL at 4 hours after ingestion, >= 75 ug/mL at 8 hours after ingestion, >= 35 ug/mL at 12 hours after ingestion.
Day(s) and Time(s) Performed
As ordered. Turn around time four hours.