Useful For
Identify and characterize the following:
• Reactive lymphocytosis vs chronic lymphocytic leukemia (CLL)
• CLL vs mantle cell lymphoma
• Prolymphocytic leukemia vs lymphoblastic leukemia large granular lymphocyte proliferations, T-γ lymphoproliferative disease, natural killer cell proliferations, T-cell CLL, T-cell γ/δ proliferations
• Sézary syndrome
• Non-Hodgkin lymphoma
• Adult T-cell leukemia/lymphoma
Neoplastic B-cell proliferations (chronic leukemias and lymphomas) are clonal expansions of cells that express either κ or λ immunoglobulin light chains.
Method Name
Immunophenotyping by flow cytometry
Important Note
Specimens should be transported to Cytology immediately.
Aliases
Flow Cytometry,
Specimen Type
Fluid
Specimen Required
FLUID: The fluid should be fresh – no fixative added (10-20 ml is acceptable).
Specimen Minimum Volume
- a minimum of 2 mL body fluid tube is requested.
Specimen Stability Information
Specimens should be transported to Cytology immediately.
Rejected Due To
Specimen frozen; specimen in formalin or other fixative; fluid in formalin or other fixative; contaminated transport medium
Performing Laboratory
Tissue specimens for flow cytometry are sent to Integrated Oncology reference laboratory.
Exception: for patients with BlueShield of Northeastern New York health insurance only, flow cytometry specimens will be sent to Quest Diagnostics reference laboratory.
Day(s) and Time(s) Performed
Monday – Friday beginning at 8 a.m.
- The cut-off time for receiving flow cytometry specimens is 3:00 p.m. to ensure timely handling and shipping to the reference laboratory.
Analytical Time
Expected turn around time:
Integrated Oncology:
- Flow Cytometry: 2 business days
- Hematopathology Consult: 6-8 business days (If applicable)
Quest:
- Flow Cytometry: 7-8 days
Specimen Retention Time
For specimen retention, see the appropriate reference lab links below:
CPT Code Information
For CPT code information please contact:
Analytical Time
Expected turn around time:
Integrated Oncology:
- Flow Cytometry: 2 business days
- Hematopathology Consult: 6-8 business days (If applicable)
Quest:
- Flow Cytometry: 7-8 days